

Similarly, diverse studies have suggested that dysregulations in fronto-striatal neurotransmitter systems might contribute to the development of BPD. In a similar way, exercise might compensate for dysregulated catecholamine levels in ADHD and thereby improve cognitive and behavioral functioning. These extremely effective medications increase the availability of dopamine and norepinephrine in the prefrontal cortex and result in a reduction of symptoms and improvement of executive functioning in the majority of patients. Stimulants are the first-line medication in ADHD. In ADHD patients, abnormalities in fronto-striatal functioning, in particular hypoactivity in the dopaminergic and noradrenergic systems, have been related to the attentional and executive impairments. Neurophysiological effects of exercise include increased central arousal associated with elevated release of fronto-striatal neurotransmitters such as dopamine, epinephrine, norepinephrine, and serotonin. Neurophysiological effects induced by physical exercise

On this basis, we provide a first attempt to discuss potential benefits of exercise for BPD and encourage research endeavours. Finally, we discuss overlapping symptoms and neurophysiological substrates of ADHD and borderline personality disorder (BPD). We complement previous reviews by providing a comprehensive overview on effects of different types of exercise on behavioral, cognitive, and neurophysiological parameters in ADHD, including the most recent studies in children, adolescents, and adult patients. We then review results from studies with different experimental approaches (i.e., acute effects and long-term interventions) to investigate the effectiveness of exercise in improving ADHD symptoms. In the following paper, we first provide a short overview on neurophysiological mechanisms suggested to underpin the beneficial effects of exercise on cognition and behavior. Interestingly, the neurophysiological changes found to be induced by exercise considerably overlap with the neuropathological mechanisms implicated in ADHD. Moreover, an association between increased exercise levels and alleviated ADHD symptoms in the general population has been found. Improvements in neurobehavioral functions have been demonstrated, including reduced impulsivity and hyperactivity, improved attention, and enhanced performance on executive functioning tasks. In addition, a growing body of literature suggests beneficial effects of exercise on symptoms of attention deficit hyperactivity disorder (ADHD). Physical exercise is known to have positive effects on general health and well-being, to bear potential to improve mood and quality of life, and to reduce stress responses.
